The direct ICC analysis of BM from the same patients revealed 16.8% positive.The ITC detection differed both quantitatively and qualitatively between BM and PB, as samples with high numbers of ITC in BM were still negative in PB.So to protect this sensitivity, they develop unusually strong boundaries. Noninvolvement, being just an observer, is one way of insuring that one is not invaded. Fives, Sixes and Sevens are all fear-based; but the specific fear of the Five is of being invaded, of being overwhelmed.Their island is protected by distance, not by hostility or placation. They are frequently highly intelligent (any number can be intelligent), but their intelligence is both a gift and a means of handling the world. If the baseball game is on Sunday, they mentally rehearse it on Friday and Saturday, play on Sunday and replay it in their minds on Monday and Tuesday.I have it on dubious authority that a Five invented instant replay.Only when they get it into their mind does it become real.They actually care for one another but they fight all the time.
Analysis of PB results showed that 25.3% had ≥ 1 tumor cell detected by the RARE procedure, compared with 5.2% after direct ICC analysis, analyzing a 10-fold larger volume by the RARE procedure.
The clinical significance of ITC in blood still needs to be established.
However, the easy access of peripheral blood, and the increased sensitivity obtained by increasing the sample volume with the RARE procedure, suggests that the value of peripheral blood analysis should be tested in parallel in studies where ITC detection in BM is performed.
There they can exercise their gifts of analysis and synthesis and make sense of their experiences.
Many Fives are excellent writers because they are keen observers, they can make minute analyses and relate what they saw to all the rest of the information they have. And while they are distant, they are also objective.
They don't allow emotion to cloud their judgment --easy for them, they're not involved! The story line is simple: Stephan, a violin repairman is in partnership with a man who divorces and begins to live with a beautiful violinist.